Can i use Socket.io in Fuse?

If can do, so i should using it like common javascript file?

The short answer is no.

Socket.io is requiring more than 120 javascript file from the node framework. Fuse is running in a minimal JavaScript environment, and not in a node environment. For instance the process api is not available, and would be some work to polyfill.

https://www.fusetools.com/community/forums/show_and_tell/socketio